Expression of TNF, IL1B, and NOS2 in the neural cell after induced by Porphyromonas gingivalis with and without coating antibody anti-Porphyromonas gingivalis
نویسندگان
چکیده
Porphyromonas gingivalis has virulence factors such as gingipain and lipopolysaccharide, causing bacteremia to reach the brain activate neuroinflammatory release cytokines. This study analyzed effect of co-culture neuron cells with P. gingivalis coated anti-P. antibodies against cytokines produced by cells. The gene expressions TNF, IL1B, NOS2 in neurons was evaluated using RT-qPCR. results showed that antibody before could decrease expression TNF, IL1B, and cells.
منابع مشابه
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ژورنال
عنوان ژورنال: F1000Research
سال: 2021
ISSN: ['2046-1402']
DOI: https://doi.org/10.12688/f1000research.26749.2